July 2017 Member Publications

Selected Publications

Navigating the Future of Cardiovascular Drug Development-Leveraging Novel Approaches to Drive Innovation and Drug Discovery: Summary of Findings from the Novel Cardiovascular Therapeutics Conference. Povsic TJ, Scott R, Mahaffey KW, Blaustein R, Edelberg JM, Lefkowitz MP, Solomon SD, Fox JC, Healy KE, Khakoo AY, Losordo DW, Malik FI, Monia BP, Montgomery RL, Riesmeyer J, Schwartz GG, Zelenkofske SL, Wu JC, Wasserman SM, Roe MT. Cardiovasc Drugs Ther. 2017 Jul 22.

Alternative Strategy for Biventricular Assist Device in an Infant With Hypertrophic Cardiomyopathy. Dykes JC, Reinhartz O, Almond CS, Yarlagadda V, Murray J, Rosenthal DN, Maeda K. Ann Thorac Surg. 2017 Aug;104(2):e185-e186.

Unreliable Observations from a Confounded Analysis of a Skewed Database. Steg PG, Harrington RA, Himmelmann A, James SK, Pieper KS, Wallentin L. Am J Med. 2017 Aug;130(8):e355-e356.

Spatial relationship of sites for atrial fibrillation drivers and atrial tachycardia in patients with both arrhythmias. Baykaner T, Zaman JAB, Rogers AJ, Navara R, AlHusseini M, Borne RT, Park S, Wang PJ, Krummen DE, Sauer WH, Narayan SM. Int J Cardiol. 2017 Jul 14. S0167-5273(17)31816-8.

Bioacoustic-enabled patterning of human iPSC-derived cardiomyocytes into 3D cardiac tissue. Serpooshan V, Chen P, Wu H, Lee S, Sharma A, Hu DA, Venkatraman S, Ganesan AV, Usta OB, Yarmush M, Yang F, Wu JC, Demirci U, Wu SM. Biomaterials. 2017 Jul;131:47-57.

Identification of a hybrid myocardial zone in the mammalian heart after birth. Tian X, Li Y, He L, Zhang H, Huang X, Liu Q, Pu W, Zhang L, Li Y, Zhao H, Wang Z, Zhu J, Nie Y, Hu S, Sedmera D, Zhong TP, Yu Y, Zhang L, Yan Y, Qiao Z, Wang QD, Wu SM, Pu WT, Anderson RH, Zhou B. Nat Commun. 2017 Jul 20;8(1):87.

Induced Pluripotent Stem Cell-Derived Endothelial Cells in Insulin Resistance and Metabolic Syndrome. Carcamo-Orive I, Huang NF, Quertermous T, Knowles JW. Arterioscler Thromb Vasc Biol. 2017 Jul 20.

Accuracy of Fractional Flow Reserve Measurements in Clinical Practice: Observations From a Core Laboratory Analysis. Matsumura M, Johnson NP, Fearon WF, Mintz GS, Stone GW, Oldroyd KG, De Bruyne B, Pijls NHJ, Maehara A, Jeremias A. JACC Cardiovasc Interv. 2017 Jul 24;10(14):1392-1401.

Exercise Training Improves Ventilatory Efficiency in Patients With a Small Abdominal Aortic Aneurysm: A RANDOMIZED CONTROLLED STUDY. Lima RM, Vainshelboim B, Ganatra R, Dalman R, Chan K, Myers J. J Cardiopulm Rehabil Prev. 2017 Jul 19.

A BAG3 chaperone complex maintains cardiomyocyte function during proteotoxic stress. Judge LM, Perez-Bermejo JA, Truong A, Ribeiro AJ, Yoo JC, Jensen CL, Mandegar MA, Huebsch N, Kaake RM, So PL, Srivastava D, Pruitt BL, Krogan NJ, Conklin BR. JCI Insight. 2017 Jul 20;2(14).

The microvascular niche instructs T cells in large vessel vasculitis via the VEGF-Jagged1-Notch pathway. Wen Z, Shen Y, Berry G, Shahram F, Li Y, Watanabe R, Liao YJ, Goronzy JJ, Weyand CM. Sci Transl Med. 2017 Jul 19;9(399).

CRISPR-Mediated Integration of Large Gene Cassettes Using AAV Donor Vectors. Bak RO, Porteus MH. Cell Rep. 2017 Jul 18;20(3):750-756.

Hypertrophic cardiomyopathy and the myosin mesa: viewing an old disease in a new light. Trivedi DV, Adhikari AS, Sarkar SS, Ruppel KM, Spudich JA. Biophys Rev. 2017 Jul 17.

Discovery of Novel Human Gene Regulatory Modules from Gene Co-expression and Promoter Motif Analysis. Ma S, Snyder M, Dinesh-Kumar SP. Sci Rep. 2017 Jul 17;7(1):5557.

Bridge to Success: A Better Method of Cryoablation for Atrioventricular Nodal Reentrant Tachycardia in Children. Reddy CD, Ceresnak SR, Motonaga KS, Avasarala K, Feller C, Trela A, Hanisch D, Dubin AM. Heart Rhythm. 2017 Jul 14.

Optimizing the analysis strategy for the CANVAS Program: A prespecified plan for the integrated analyses of the CANVAS and CANVAS-R trials. Neal B, Perkovic V, Mahaffey KW, Fulcher G, Erondu N, Desai M, Shaw W, Law G, Walton MK, Rosenthal N, de Zeeuw D, Matthews DR; CANVAS Program collaborative group. Diabetes Obes Metab. 2017 Jul;19(7):926-935.

Anisotropic microfibrous scaffolds enhance the organization and function of cardiomyocytes derived from induced pluripotent stem cells. Wanjare M, Hou L, Nakayama KH, Kim JJ, Mezak NP, Abilez OJ, Tzatzalos E, Wu JC, Huang NF. Biomater Sci. 2017 Jul 17.

The importance of capillary density-stroke work mismatch for right ventricular adaptation to chronic pressure overload. Noly PE, Haddad F, Arthur-Ataam J, Langer N, Dorfmüller P, Loisel F, Guihaire J, Decante B, Lamrani L, Fadel E, Mercier O. J Thorac Cardiovasc Surg. 2017 Jun 15.

Targeting weight loss interventions to reduce cardiovascular complications of type 2 diabetes: a machine learning-based post-hoc analysis of heterogeneous treatment effects in the Look AHEAD trial. Baum A, Scarpa J, Bruzelius E, Tamler R, Basu S, Faghmous J. Lancet Diabetes Endocrinol. 2017 Jul 12.

Clinical Effectiveness of Hydralazine-Isosorbide Dinitrate in African-American Patients With Heart Failure. Ziaeian B, Fonarow GC, Heidenreich PA. JACC Heart Fail. 2017 Jul 12. S2213-1779(17)30278-0.

Comparison of Non-Coding RNAs in Exosomes and Functional Efficacy of Human Embryonic Stem Cell- Versus Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Lee WH, Chen W, Shao NY, Xiao D, Qin X, Baker N, Bae HRM, Shukla P, Wu H, Kodo K, Ong SG, Wu JC. Stem Cells. 2017 Jul 14.

Accelerometry: Improving Objective Assessments of Therapeutic Impact in Pediatric Pulmonary Arterial Hypertension. Austin ED, Feinstein JA. Am J Respir Crit Care Med. 2017 Jul 15;196(2):127-129.

Assessment of bioresorbable scaffold with a novel high-definition 60 MHz IVUS imaging system: Comparison with 40-MHz IVUS referenced to optical coherence tomography. Okada K, Kitahara H, Mitsutake Y, Tanaka S, Kimura T, Yock PG, Fitzgerald PJ, Ikeno F, Honda Y. Catheter Cardiovasc Interv. 2017 Jul 14.

DNA binding drives the association of BRG1/hBRM bromodomains with nucleosomes. Morrison EA, Sanchez JC, Ronan JL, Farrell DP, Varzavand K, Johnson JK, Gu BX, Crabtree GR, Musselman CA. Nat Commun. 2017 Jul 14;8:16080.

Comprehensive Multi-Dimensional MRI for the Simultaneous Assessment of Cardiopulmonary Anatomy and Physiology. Cheng JY, Zhang T, Alley MT, Uecker M, Lustig M, Pauly JM, Vasanawala SS. Sci Rep. 2017 Jul 13;7(1):5330.

Using Commercial Programs for Lifestyle Intervention: Not Reinventing the Wheel. Maron DJ, Sandhu AT. J Am Coll Cardiol. 2017 Jul 18;70(3):328-330.

Comparison of Fatal or Irreversible Events With Extended-Duration Betrixaban Versus Standard Dose Enoxaparin in Acutely Ill Medical Patients: An APEX Trial Substudy. Gibson CM, Korjian S, Chi G, Daaboul Y, Jain P, Arbetter D, Goldhaber SZ, Hull R, Hernandez AF, Lopes RD, Gold A, Cohen AT, Harrington RA; APEX Investigators. J Am Heart Assoc. 2017 Jul 11;6(7).

Large-scale physical activity data reveal worldwide activity inequality. Althoff T, Sosič R, Hicks JL, King AC, Delp SL, Leskovec J. Nature. 2017 Jul 20;547(7663):336-339.

Myocardial Bridges on Coronary Computed Tomography Angiography　- Correlation With Intravascular Ultrasound and Fractional Flow Reserve. Forsdahl SH, Rogers IS, Schnittger I, Tanaka S, Kimura T, Pargaonkar VS, Chan FP, Fleischmann D, Tremmel JA, Becker HC. Circ J. 2017 Jul 7.

Contractile reserve and cardiopulmonary exercise parameters in patients with dilated cardiomyopathy, the two dimensions of exercise testing. Moneghetti KJ, Kobayashi Y, Christle JW, Ariyama M, Vrtovec B, Kouznetsova T, Wilson A, Ashley E, Wheeler MT, Myers J, Haddad F. Echocardiography. 2017 Jul 6.

Gaining comprehensive biological insight into the transcriptome by performing a broad-spectrum RNA-seq analysis. Sahraeian SME, Mohiyuddin M, Sebra R, Tilgner H, Afshar PT, Au KF, Bani Asadi N, Gerstein MB, Wong WH, Snyder MP, Schadt E, Lam HYK. Nat Commun. 2017 Jul 5;8(1):59.

Risk and Consequences of Atrial Fibrillation: It's in the Jeans, Not the Genes. Turakhia MP. JAMA Cardiol. 2017 Jul 5.

Microfluidic-based mini-metagenomics enables discovery of novel microbial lineages from complex environmental samples. Yu FB, Blainey PC, Schulz F, Woyke T, Horowitz MA, Quake SR. Elife. 2017 Jul 5;6.

Molecular Mechanisms of Sodium-Sensitive Hypertension in the Metabolic Syndrome. Nizar JM, Bhalla V. Curr Hypertens Rep. 2017 Aug;19(8):60.

New Generalized Equation for Predicting Maximal Oxygen Uptake (from the Fitness Registry and the Importance of Exercise National Database). Kokkinos P, Kaminsky LA, Arena R, Zhang J, Myers J. Am J Cardiol. 2017 Jun 1. S0002-9149(17)30873-1.

Myocardial bridges: Overview of diagnosis and management. Rogers IS, Tremmel JA, Schnittger I. Congenit Heart Dis. 2017 Jul 3.

Associations Between Self-Reported Physical Activity and Physical Performance Measures Over Time in Postmenopausal Women: The Women's Health Initiative. Laddu DR, Wertheim BC, Garcia DO, Brunner R, Groessl E, Shadyab AH, Going SB, LaMonte MJ, Cannell B, LeBoff MS, Cauley JA, Thomson CA, Stefanick ML. J Am Geriatr Soc. 2017 Jul 4.

Changes in E-cadherin rigidity sensing regulate cell adhesion. Collins C, Denisin AK, Pruitt BL, Nelson WJ. Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):E5835-E5844.

E-cadherin and LGN align epithelial cell divisions with tissue tension independently of cell shape. Hart KC, Tan J, Siemers KA, Sim JY, Pruitt BL, Nelson WJ, Gloerich M. Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):E5845-E5853.

Needs-Based Innovation in Interventional Radiology: The Biodesign Process. Steinberger JD, Denend L, Azagury DE, Brinton TJ, Makower J, Yock PG. Tech Vasc Interv Radiol. 2017 Jun;20(2):84-89.

Thalidomide treatment prevents chronic graft rejection after aortic transplantation in rats. Miller KK, Wang D, Hu X, Hua X, Deuse T, Neofytou E, Renne T, Velden J, Reichenspurner H, Schrepfer S, Bernstein D. Transpl Int. 2017 Jul 3.

Outdoor Reproducibility of a 1-km Treadmill Walking Test to Predict Peak Oxygen Uptake in Cardiac Patients. Grazzi G, Chiaranda G, Myers J, Pasanisi G, Lordi R, Conconi F, Mazzoni G. J Cardiopulm Rehabil Prev. 2017 Jun 30.

Circulating Biomarkers to Identify Responders in Cardiac Cell therapy. Jokerst JV, Cauwenberghs N, Kuznetsova T, Haddad F, Sweeney T, Hou J, Rosenberg-Hasson Y, Zhao E, Schutt R, Bolli R, Traverse JH, Pepine CJ, Henry TD, Schulman IH, Moyé L, Taylor DA, Yang PC. Sci Rep. 2017 Jun 30;7(1):4419.