November 2016 Member Publications

Selected Publications

1)     Cholesterol, Cardiovascular Risk, Statins, PCSK9 Inhibitors, and the Future of LDL-C Lowering.
Rodriguez F, Harrington RA.
JAMA. 2016 Nov 15;316(19):1967-1968.

2)     The Role of Dual-Phase Cone-Beam CT in Predicting Short-Term Response after Transarterial Chemoembolization for Hepatocellular Carcinoma.
Müller K, Datta S, Gehrisch S, Ahmad M, Mohammed MA, Rosenberg J, Hwang GL, Louie JD, Sze DY, Kothary N.
J Vasc Interv Radiol. 2016 Nov 30.

3)     Cost-Effectiveness of Left Ventricular Assist Devices in Ambulatory Patients With Advanced Heart Failure.
Baras Shreibati J, Goldhaber-Fiebert JD, Banerjee D, Owens DK, Hlatky MA.
JACC Heart Fail. 2016 Nov 30.

4)     Absence of Oral Anticoagulation and Subsequent Outcomes Among Outpatients with Atrial Fibrillation.
Hess PL, Kim S, Fonarow GC, Thomas L, Singer DE, Freeman JV, Gersh BJ, Ansell J, Kowey PR, Mahaffey KW, Chan PS, Steinberg BA, Peterson ED, Piccini JP; Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) Patients and Investigators.
Am J Med. 2016 Nov 22.

5)     Predictors and Prognostic Implications of Incident Heart Failure in Patients With Prevalent Atrial Fibrillation.
Pandey A, Kim S, Moore C, Thomas L, Gersh B, Allen LA, Kowey PR, Mahaffey KW, Hylek E, Peterson ED, Piccini JP, Fonarow GC; ORBIT-AF (Outcomes Registry for Better Informed Treatment of Atrial Fibrillation) Investigators and Patients.
JACC Heart Fail. 2016 Nov 30.

6)     Evaluation of Ischemic and Bleeding Risks Associated With 2 Parenteral Antiplatelet Strategies Comparing Cangrelor With Glycoprotein IIb/IIIa Inhibitors: An Exploratory Analysis From the CHAMPION Trials.
Vaduganathan M, Harrington RA, Stone GW, Deliargyris EN, Steg PG, Gibson CM, Hamm CW, Price MJ, Menozzi A, Prats J, Elkin S, Mahaffey KW, White HD, Bhatt DL.
JAMA Cardiol. 2016 Nov 30.

7)     A Prospective Natural History Study of Coronary Atherosclerosis Using Fractional Flow Reserve.
Barbato E, Toth GG, Johnson NP, Pijls NH, Fearon WF, Tonino PA, Curzen N, Piroth Z, Rioufol G, Jüni P, De Bruyne B.
J Am Coll Cardiol. 2016 Nov 29;68(21):2247-2255.

8)     MicroRNA-210 Enhances Fibrous Cap Stability in Advanced Atherosclerotic Lesions.
Eken SM, Jin H, Chernogubova E, Li Y, Simon N, Sun C, Korzunowicz G, Busch A, Bäcklund A, Österholm C, Razuvaev A, Renné T, Eckstein HH, Pelisek J, Eriksson P, Gonzalez Diez M, Matic Perisic LP, Schellinger IN, Raaz U, Leeper NJ, Hansson GK, Paulsson-Berne G, Hedin U, Maegdefessel L.
Circ Res. 2016 Nov 28.

9)     Rehospitalization after pediatric heart transplantation: Incidence, indications, and outcomes.
Hollander SA, McElhinney DB, Almond CS, McDonald N, Chen S, Kaufman BD, Bernstein D, Rosenthal DN.
Pediatr Transplant. 2016 Nov 27.

10)   Quantification of motion of the thoracic aorta after ascending aortic repair of type-A dissection.
Suh GY, Fleischmann D, Beygui RE, Cheng CP.
Int J Comput Assist Radiol Surg. 2016 Nov 23.

11)   Incidence, risk factors, and outcomes of acute kidney injury in adults undergoing surgery for congenital heart disease.
Kwiatkowski DM, Price E, Axelrod DM, Romfh AW, Han BS, Sutherland SM, Krawczeski CD.
Cardiol Young. 2016 Nov 21:1-8.

12)   Transcriptomic Profiling Maps Anatomically Patterned Subpopulations among Single Embryonic Cardiac Cells.
Li G, Xu A, Sim S, Priest JR, Tian X, Khan T, Quertermous T, Zhou B, Tsao PS, Quake SR, Wu SM.
Dev Cell. 2016 Nov 21;39(4):491-507.

13)   Cardiorespiratory Fitness and Incidence of Major Adverse Cardiovascular Events in US Veterans: A Cohort Study.
Kokkinos PF, Faselis C, Myers J, Narayan P, Sui X, Zhang J, Lavie CJ, Moore H, Karasik P, Fletcher R.
Mayo Clin Proc. 2016 Nov 19.

14)   Associations between a Genetic Risk Score for Clinical CAD and Early Stage Lesions in the Coronary Artery and the Aorta.
Salfati EL, Herrington DM, Assimes TL.
PLoS One. 2016 Nov 18;11(11).

15)   CRISPR/Cas9 β-globin gene targeting in human haematopoietic stem cells.
Dever DP, Bak RO, Reinisch A, Camarena J, Washington G, Nicolas CE, Pavel-Dinu M, Saxena N, Wilkens AB, Mantri S, Uchida N, Hendel A, Narla A, Majeti R, Weinberg KI, Porteus MH.
Nature. 2016 Nov 17;539(7629):384-389.

16)   Meta-Analysis Comparing Established Risk Prediction Models (EuroSCORE II, STS Score, and ACEF Score) for Perioperative Mortality During Cardiac Surgery.
Sullivan PG, Wallach JD, Ioannidis JP.
Am J Cardiol. 2016 Nov 15;118(10):1574-1582.

17)   Cost-Effectiveness of Sacubitril-Valsartan in Patients With Heart Failure With Reduced Ejection Fraction.
Sandhu AT, Ollendorf DA, Chapman RH, Pearson SD, Heidenreich PA.
Ann Intern Med. 2016 Nov 15;165(10):681-689.

18)   Portable, one-step, and rapid GMR biosensor platform with smartphone interface.
Choi J, Gani AW, Bechstein DJ, Lee JR, Utz PJ, Wang SX.
Biosens Bioelectron. 2016 Nov 15;85:1-7.

19)   Warfarin utilisation and anticoagulation control in patients with atrial fibrillation and chronic kidney disease.
Yang F, Hellyer JA, Than C, Ullal AJ, Kaiser DW, Heidenreich PA, Hoang DD, Winkelmayer WC, Schmitt S, Frayne SM, Phibbs CS, Turakhia MP.
Heart. 2016 Nov 15.

20)   A modified implantation technique of left ventricular assist device: optimal outflow tract positioning.
Shudo Y, Choi CW, Woo YJ, Ha RV.
Int J Cardiol. 2016 Nov 15;223:776-778.

21)   Blood Stem Cell Activity Is Arrested by Th1-Mediated Injury Preventing Engraftment following Nonmyeloablative Conditioning.
Müller AM, Florek M, Kohrt HE, Küpper NJ, Filatenkov A, Linderman JA, Hadeiba H, Negrin RS, Shizuru JA.
J Immunol. 2016 Nov 15;197(10):4151-4162.

22)   Telomere shortening and metabolic compromise underlie dystrophic cardiomyopathy.
Chang AC, Ong SG, LaGory EL, Kraft PE, Giaccia AJ, Wu JC, Blau HM.
Proc Natl Acad Sci U S A. 2016 Nov 15;113(46):13120-13125.

23)   Interactive Effects of Aerobic Fitness, Strength, and Obesity on Mortality in Men.
Crump C, Sundquist J, Winkleby MA, Sundquist K.
Am J Prev Med. 2016 Nov 14. pii: S0749-3797(16)30508-6.

24)   Extended-Duration Betrixaban Reduces the Risk of Stroke Versus Standard-Dose Enoxaparin Among Hospitalized Medically Ill Patients: An APEX Trial Substudy (Acute Medically Ill Venous Thromboembolism Prevention With Extended Duration Betrixaban).
Gibson CM, Chi G, Halaby R, Korjian S, Daaboul Y, Jain P, Arbetter D, Goldhaber SZ, Hull R, Hernandez AF, Gold A, Bandman O, Harrington RA, Cohen AT; APEX Investigators.
Circulation. 2016 Nov 14.

25)   Genetic cardiovascular risk prediction: are we already there?
Assimes TL, Goldstein BA.
Eur Heart J. 2016 Nov 14;37(43):3279-3281.

26)   Ticagrelor Compared With Clopidogrel in Patients with Prior Lower Extremity Revascularization for Peripheral Artery Disease.
Jones WS, Baumgartner I, Hiatt WR, Heizer G, Conte MS, White CJ, Berger JS, Held P, Katona BG, Mahaffey KW, Norgren L, Blomster J, Millegård M, Reist C, Patel MR, Fowkes GR; International Steering Committee and Investigators of the EUCLID Trial.
Circulation. 2016 Nov 13.

27)   Association Between Intensity of Statin Therapy and Mortality in Patients With Atherosclerotic Cardiovascular Disease.
Rodriguez F, Maron DJ, Knowles JW, Virani SS, Lin S, Heidenreich PA.
JAMA Cardiol. 2016 Nov 9.

28)   Adaptive Immunity Dysregulation in Acute Coronary Syndromes: From Cellular and Molecular Basis to Clinical Implications.
Flego D, Liuzzo G, Weyand CM, Crea F.
J Am Coll Cardiol. 2016 Nov 8;68(19):2107-2117.

29)   Patient-Specific and Genome-Edited Induced Pluripotent Stem Cell-Derived Cardiomyocytes Elucidate Single-Cell Phenotype of Brugada Syndrome.
Liang P, Sallam K, Wu H, Li Y, Itzhaki I, Garg P, Zhang Y, Vermglinchan V, Lan F, Gu M, Gong T, Zhuge Y, He C, Ebert AD, Sanchez-Freire V, Churko J, Hu S, Sharma A, Lam CK, Scheinman MM, Bers DM, Wu JC.
J Am Coll Cardiol. 2016 Nov 8;68(19):2086-2096.

30)   Deep Learning Automates the Quantitative Analysis of Individual Cells in Live-Cell Imaging Experiments.
Van Valen DA, Kudo T, Lane KM, Macklin DN, Quach NT, DeFelice MM, Maayan I, Tanouchi Y, Ashley EA, Covert MW.
PLoS Comput Biol. 2016 Nov 4;12(11).

31)   Inhibition of Apoptosis Overcomes Stage-Related Compatibility Barriers to Chimera Formation in Mouse Embryos.
Masaki H, Kato-Itoh M, Takahashi Y, Umino A, Sato H, Ito K, Yanagida A, Nishimura T, Yamaguchi T, Hirabayashi M, Era T, Loh KM, Wu SM, Weissman IL, Nakauchi H.
Cell Stem Cell. 2016 Nov 3;19(5):587-592.

32)   Loss of smooth muscle cell hypoxia inducible factor-1α underlies increased vascular contractility in pulmonary hypertension.
Barnes EA, Chen CH, Sedan O, Cornfield DN.
FASEB J. 2016 Nov 3.

33)   Effect of Significant Weight Change on Inappropriate Implantable Cardioverter-Defibrillator Therapy.
Daimee UA, Biton Y, Aktas MK, Zannad F, Klein H, Szepietowska B, McNitt S, Polonsky B, Wang PJ, Zareba W, Moss AJ, Kutyifa V.
Pacing Clin Electrophysiol. 2016 Nov 3.

34)   International Collaborative Partnership for the Study of Atrial Fibrillation (INTERAF): Rationale, Design, and Initial Descriptives.
Hsu JC, Akao M, Abe M, Anderson KL, Avezum A, Glusenkamp N, Kohsaka S, Lane DA, Lip GY, Ma CS, Masoudi FA, Potpara TS, Siong TW, Turakhia MP, Tse HF, Rumsfeld JS, Maddox TM.
J Am Heart Assoc. 2016 Nov 2;5(11).

35)   Regulating Stem Cell Secretome Using Injectable Hydrogels with In Situ Network Formation.
Cai L, Dewi RE, Goldstone AB, Cohen JE, Steele AN, Woo YJ, Heilshorn SC.
Adv Healthc Mater. 2016 Nov;5(21):2758-2764.

36)   How well does physician risk assessment predict stroke and bleeding in atrial fibrillation? Results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF).
Steinberg BA, Shrader P, Kim S, Thomas L, Fonarow GC, Ansell J, Kowey PR, Singer DE, Gersh BJ, Mahaffey KW, Peterson ED, Piccini JP; ORBIT-AF Investigators and Patients.
Am Heart J. 2016 Nov;181:145-152.

37)   Depressive Symptoms, Cardiac Disease Severity, and Functional Status in Patients With Coronary Artery Disease (from the Heart and Soul Study).
Schopfer DW, Regan M, Heidenreich PA, Whooley MA.
Am J Cardiol. 2016 Nov 1;118(9):1287-1292.

38)   Metabolic Markers to Predict Incident Diabetes Mellitus in Statin-Treated Patients (from the Treating to New Targets and the Stroke Prevention by Aggressive Reduction in Cholesterol Levels Trials).
Kohli P, Knowles JW, Sarraju A, Waters DD, Reaven G.
Am J Cardiol. 2016 Nov 1;118(9):1275-1281.

39)   Is minimally invasive thoracoscopic surgery the new benchmark for treating mitral valve disease?
Goldstone AB, Woo YJ.
Ann Cardiothorac Surg. 2016 Nov;5(6):567-572.

40)   Magnetic Resonance Imaging of Cardiac Strain Pattern Following Transplantation of Human Tissue Engineered Heart Muscles.
Qin X, Riegler J, Tiburcy M, Zhao X, Chour T, Ndoye B, Nguyen M, Adams J, Ameen M, Denney TS Jr, Yang PC, Nguyen P, Zimmermann WH, Wu JC.
Circ Cardiovasc Imaging. 2016 Nov;9(11).

41)   Vorapaxar: emerging evidence and clinical questions in a new era of PAR-1 inhibition.
Ungar L, Rodriguez F, Mahaffey KW.
Coron Artery Dis. 2016 Nov;27(7):604-15.

42)   Novel Therapies for Familial Hypercholesterolemia.
Parizo J, Sarraju A, Knowles JW.
Curr Treat Options Cardiovasc Med. 2016 Nov;18(11):64

43)   Exploratory insights from the right-sided electrocardiogram following prolonged endurance exercise.
Lord R, George K, Somauroo J, Jain N, Reese K, Hoffman MD, Haddad F, Ashley E, Jones H, Oxborough D.
Eur J Sport Sci. 2016 Nov;16(8):1014-22.

44)   Terminating atrial fibrillation by cooling the heart.
Narayan SM, Baykaner T, Sahli Costabal F, Kuhl E.
Heart Rhythm. 2016 Nov;13(11):2259-2260

45)   Radial access in patients with acute coronary syndrome without persistent ST-segment elevation: Systematic review, collaborative meta-analysis, and meta-regression.
Andò G, Porto I, Montalescot G, Bolognese L, Trani C, Oreto G, Harrington RA, Bhatt DL.
Int J Cardiol. 2016 Nov 1;222:1031-9.

46)   Apelin-13 infusion salvages the peri-infarct region to preserve cardiac function after severe myocardial injury.
Chung WJ, Cho A, Byun K, Moon J, Ge X, Seo HS, Moon E, Dash R, Yang PC.
Int J Cardiol. 2016 Nov 1;222:361-7.

47)   Early Left Ventricular Dysfunction is Associated with Cardiac Allograft Vasculopathy and Late Mortality After Heart Transplantation.
Okada K, Honda Y, Luikart H, Yock P, Fitzgerald PJ, Yeung A, Valantine H, Khush K, Fearon W.
J Am Coll Cardiol. 2016 Nov 1;68(18S):B331.

48)   Baseline growth differentiation factor 15 (GDF15) is an independent predictor of reverse left atrial remodeling and mortality at 1-year following Transcatheter Aortic Valve Replacement.
Kim J, Kobayashi Y, Brenner D, Moneghetti K, O'Malley R, Dao C, Vu T, Schnittger I, Liang D, Wu J, Fischbein M, Lee A, Miller DC, Yeung A, Haddad F, Fearon W.
J Am Coll Cardiol. 2016 Nov 1;68(18S):B298.

49)   Intravascular Ultrasound Guidance Improves the Long-term Prognosis in Patients with Unprotected Left Main Coronary Artery Disease Undergoing Percutaneous Coronary Intervention.
Tang Y, Tian J, Guan C, Wang W, Zhang K, Chen J, Wu Y, Yan H, Zhao Y, Qiao S, Yang Y, Mintz G, Xu B.
J Am Coll Cardiol. 2016 Nov 1;68(18S):B224.

50)   Comparison between Instantaneous Wave-Free Ratio and Fractional Flow Reserve versus Morphometric Assessments by Intracoronary Imaging Devices.
Matsushita K, Hibi K, Okada K, Matsuzawa Y, Kimura Y, Maejima N, Iwahashi N, Moritz A, Ebina T, Fitzgerald PJ, Honda Y, Kimura K.
J Am Coll Cardiol. 2016 Nov 1;68(18S):B218.

51)   Multi-Center, Randomized Evaluation of the Elixir DESyne® Novolimus Eluting Coronary Stent System with Biodegradable Polymer Compared to a Zotarolimus-Eluting Coronary Stent System: Final 5-Year Results from the EXCELLA BD Study.
Verheye S, Abizaid A, Botelho R, Costa R, Tanajura LF, Waseda K, Morrison L, Toyloy S, Fitzgerald PJ, Schofer J.
J Am Coll Cardiol. 2016 Nov 1;68(18S):B185.

52)   Bioresorbable Vascular Scaffold for the Treatment of Tapered Coronary Lesions.
Okada K, Kitahara H, Yock P, Fitzgerald PJ, Kimura T, Honda Y.
J Am Coll Cardiol. 2016 Nov 1;68(18S):B165.

53)   Effect of Sapien-3 Transcatheter Valve Implant on Health Status in Patients with Severe Aortic Stenosis at Intermediate Surgical Risk: Results from the PARTNER S3i Trial.
Baron S, Alu M, Thourani V, Kodali S, Arnold S, Chinnakondepali K, Magnuson E, Wang K, Pichard A, Babaliaros V, George I, Miller DC, Tuzcu EM, Greason K, Herrmann H, Smith C, Leon M, Cohen D.
J Am Coll Cardiol. 2016 Nov 1;68(18S):B14.

54)   Scar Homogenization Versus Limited-Substrate Ablation in Patients With Nonischemic Cardiomyopathy and Ventricular Tachycardia.
Gökoğlan Y, Mohanty S, Gianni C, Santangeli P, Trivedi C, Güneş MF, Bai R, Al-Ahmad A, Gallinghouse GJ, Horton R, Hranitzky PM, Sanchez JE, Beheiry S, Hongo R, Lakkireddy D, Reddy M, Schweikert RA, Dello Russo A, Casella M, Tondo C, Burkhardt JD, Themistoclakis S, Di Biase L, Natale A.
J Am Coll Cardiol. 2016 Nov 1;68(18):1990-1998.

55)   Left Atrial Appendage Isolation in Patients With Longstanding Persistent AF Undergoing Catheter Ablation: BELIEF Trial.
Di Biase L, Burkhardt JD, Mohanty P, Mohanty S, Sanchez JE, Trivedi C, Güneş M, Gökoğlan Y, Gianni C, Horton RP, Themistoclakis S, Gallinghouse GJ, Bailey S, Zagrodzky JD, Hongo RH, Beheiry S, Santangeli P, Casella M, Dello Russo A, Al-Ahmad A, Hranitzky P, Lakkireddy D, Tondo C, Natale A.
J Am Coll Cardiol. 2016 Nov 1;68(18):1929-1940.

56)   Pediatric Echocardiography by Work Relative Value Units: Is Study Complexity Adequately Captured?
Balasubramanian S, Kipps AK, Smith SN, Tacy TA, Selamet Tierney ES.
J Am Soc Echocardiogr. 2016 Nov;29(11):1084-1091.

57)   The use of machine learning for the identification of peripheral artery disease and future mortality risk.
Ross EG, Shah NH, Dalman RL, Nead KT, Cooke JP, Leeper NJ.
J Vasc Surg. 2016 Nov;64(5):1515-1522.e3.

58)   Potential Strategies to Address the Major Clinical Barriers Facing Stem Cell Regenerative Therapy for Cardiovascular Disease: A Review.
Nguyen PK, Neofytou E, Rhee JW, Wu JC.
JAMA Cardiol. 2016 Nov 1;1(8):953-962.

59)   Comparative effectiveness and cost-effectiveness of treat-to-target versus benefit-based tailored treatment of type 2 diabetes in low-income and middle-income countries: a modelling analysis.
Basu S, Shankar V, Yudkin JS.
Lancet Diabetes Endocrinol. 2016 Nov;4(11):922-932.

60)   Simul-seq: combined DNA and RNA sequencing for whole-genome and transcriptome profiling.
Reuter JA, Spacek DV, Pai RK, Snyder MP.
Nat Methods. 2016 Nov;13(11):953-958.

61)   Is There a Difference in Tachycardia Cycle Length during SVT in Children with AVRT and AVNRT?
Mills MF, Motonaga KS, Trela A, Dubin AM, Avasarala K, Ceresnak SR.
Pacing Clin Electrophysiol. 2016 Nov;39(11):1206-1212.

62)   Determining conduction patterns on a sparse electrode grid: Implications for the analysis of clinical arrhythmias.
Vidmar D, Narayan SM, Krummen DE, Rappel WJ.
Phys Rev E. 2016 Nov;94(5-1):050401