December 2016 Member Publications

Selected Publications

1)     Factors Associated With and Prognostic Implications of Cardiac Troponin Elevation in Decompensated Heart Failure With Preserved Ejection Fraction: Findings From the American Heart Association Get With The Guidelines-Heart Failure Program.
Pandey A, Golwala H, Sheng S, DeVore AD, Hernandez AF, Bhatt DL, Heidenreich PA, Yancy CW, de Lemos JA, Fonarow GC.
JAMA Cardiol. 2016 Dec 28.

2)     Electrocardiographic Biomarkers for Detection of Drug-Induced Late Sodium Current Block.
Vicente J, Johannesen L, Hosseini M, Mason JW, Sager PT, Pueyo E, Strauss DG.
PLoS One. 2016 Dec 30;11(12).

3)     Long-term follow-up of patients with paroxysmal atrial fibrillation and severe left atrial scarring: comparison between pulmonary vein antrum isolation only or pulmonary vein isolation combined with either scar homogenization or trigger ablation.
Mohanty S, Mohanty P, Di Biase L, Trivedi C, Morris EH, Gianni C, Santangeli P, Bai R, Sanchez JE, Hranitzky P, Gallinghouse GJ, Al-Ahmad A, Horton RP, Hongo R, Beheiry S, Elayi CS, Lakkireddy D, Madhu Reddy Y, Viles Gonzalez JF, Burkhardt JD, Natale A.
Europace. 2016 Dec 29.

4)     Genetics: Implications for Prevention and Management of Coronary Artery Disease.
Assimes TL, Roberts R.
J Am Coll Cardiol. 2016 Dec 27;68(25):2797-2818.

5)     Overview of Balloon Approaches to AF Ablation: Some Like it Hot?
Wang PJ.
J Am Coll Cardiol. 2016 Dec 27;68(25):2758-2760.

6)     Association Between the Birth of an Infant With Major Congenital Anomalies and Subsequent Risk of Mortality in Their Mothers.
Cohen E, Horváth-Puhó E, Ray JG, Pedersen L, Adler N, Ording AG, Wise PH, Milstein A, Toft Sørensen H.
JAMA. 2016 Dec 20;316(23):2515-2524.

7)     Single Molecule Force Measurements in Living Cells Reveal a Minimally Tensioned Integrin State.
Chang AC, Mekhdjian AH, Morimatsu M, Denisin AK, Pruitt BL, Dunn AR.
ACS Nano. 2016 Dec 27;10(12):10745-10752.

8)     High-Resolution Analysis of Antibodies to Post-Translational Modifications Using Peptide Nanosensor Microarrays.
Lee JR, Haddon DJ, Gupta N, Price JV, Credo GM, Diep VK, Kim K, Hall DA, Baechler EC, Petri M, Varma M, Utz PJ, Wang SX.
ACS Nano. 2016 Dec 27;10(12):10652-10660.

9)     DIETFITS study (diet intervention examining the factors interacting with treatment success) - Study design and methods.
Stanton M, Robinson J, Kirkpatrick S, Farzinkhou S, Avery E, Rigdon J, Offringa L, Trepanowski J, Hauser M, Hartle J, Cherin R, King AC, Ioannidis JP, Desai M, Gardner CD.
Contemp Clin Trials. 2016 Dec 24.

10)   Volume of subclinical embolic infarct correlates to long-term cognitive changes after carotid revascularization.
Zhou W, Baughman BD, Soman S, Wintermark M, Lazzeroni LC, Hitchner E, Bhat J, Rosen A.
J Vasc Surg. 2016 Dec 23.

11)   Left Atrium Maximal Axial Cross-Sectional Area is a Specific Computed Tomographic Imaging Biomarker of World Health Organization Group 2 Pulmonary Hypertension.
Jivraj K, Bedayat A, Sung YK, Zamanian RT, Haddad F, Leung AN, Rosenberg J, Guo HH.
J Thorac Imaging. 2016 Dec 22.

12)   Integrated, multicohort analysis of systemic sclerosis identifies robust transcriptional signature of disease severity.
Lofgren S, Hinchcliff M, Carns M, Wood T, Aren K, Arroyo E, Cheung P, Kuo A, Valenzuela A, Haemel A, Wolters PJ, Gordon J, Spiera R, Assassi S, Boin F, Chung L, Fiorentino D, Utz PJ, Whitfield ML, Khatri P.
JCI Insight. 2016 Dec 22;1(21).

13)   Institution of Veno-arterial Extracorporeal Membrane Oxygenation Does Not Lead to Increased Wall Stress in Patients with Impaired Myocardial Function.
Koth AM, Axelrod DM, Reddy S, Roth SJ, Tacy TA, Punn R.
Pediatr Cardiol. 2016 Dec 22.

14)   The Impact of Postgraduate Health Technology Innovation Training: Outcomes of the Stanford Biodesign Fellowship.
Wall J, Hellman E, Denend L, Rait D, Venook R, Lucian L, Azagury D, Yock PG, Brinton TJ.
Ann Biomed Eng. 2016 Dec 21.

15)   Dissecting the relationship between obesity and hyperinsulinemia: Role of insulin secretion and insulin clearance.
Kim MK, Reaven GM, Kim SH.
Obesity (Silver Spring). 2016 Dec 21.

16)   Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis.
Hinson JT, Chopra A, Lowe A, Sheng CC, Gupta RM, Kuppusamy R, O'Sullivan J, Rowe G, Wakimoto H, Gorham J, Zhang K, Musunuru K, Gerszten RE, Wu SM, Chen CS, Seidman JG, Seidman CE.
Cell Rep. 2016 Dec 20;17(12):3292-3304.

17)   Comparing the vascular response in implantation of self-expanding, bare metal nitinol stents or paclitaxel-eluting nitinol stents in superficial femoral artery lesions: a serial optical frequency domain imaging study.
Miki K, Fujii K, Shibuya M, Fukunaga M, Imanaka T, Tamaru H, Nishimura M, Horimatsu T, Honda Y, Fitzgerald PJ, Masuyama T, Ishihara M.
EuroIntervention. 2016 Dec 20;12(12):1551-1558.

18)   Off-Label Dosing of Non-Vitamin K Antagonist Oral Anticoagulants and Adverse Outcomes: The ORBIT-AF II Registry.
Steinberg BA, Shrader P, Thomas L, Ansell J, Fonarow GC, Gersh BJ, Kowey PR, Mahaffey KW, Naccarelli G, Reiffel J, Singer DE, Peterson ED, Piccini JP; ORBIT-AF Investigators and Patients.
J Am Coll Cardiol. 2016 Dec 20;68(24):2597-2604.

19)   Single cell transcriptomics reveals unanticipated features of early hematopoietic precursors.
Yang J, Tanaka Y, Seay M, Li Z, Jin J, Garmire LX, Zhu X, Taylor A, Li W, Euskirchen G, Halene S, Kluger Y, Snyder MP, Park IH, Pan X, Weissman SM.
Nucleic Acids Res. 2016 Dec 20.

20)   An atlas of transcriptional, chromatin accessibility, and surface marker changes in human mesoderm development.
Koh PW, Sinha R, Barkal AA, Morganti RM, Chen A, Weissman IL, Ang LT, Kundaje A, Loh KM.
Sci Data. 2016 Dec 20;3:160109.

21)   IDEAS (Integrate, Design, Assess, and Share): A Framework and Toolkit of Strategies for the Development of More Effective Digital Interventions to Change Health Behavior.
Mummah SA, Robinson TN, King AC, Gardner CD, Sutton S.
J Med Internet Res. 2016 Dec 16;18(12).

22)   Induced pluripotent stem cell technology: a decade of progress.
Shi Y, Inoue H, Wu JC, Yamanaka S.
Nat Rev Drug Discov. 2016 Dec 16.

23)   STAMS: STRING-assisted module search for genome wide association studies and application to autism.
Hillenmeyer S, Davis LK, Gamazon ER, Cook EH, Cox NJ, Altman RB.
Bioinformatics. 2016 Dec 15;32(24):3815-3822.

24)   Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis.
Ang YS, Rivas RN, Ribeiro AJ, Srivas R, Rivera J, Stone NR, Pratt K, Mohamed TM, Fu JD, Spencer CI, Tippens ND, Li M, Narasimha A, Radzinsky E, Moon-Grady AJ, Yu H, Pruitt BL, Snyder MP, Srivastava D.
Cell. 2016 Dec 15;167(7):1734-1749.

25)   Practical ImmunoPET radiotracer design considerations for human immune checkpoint imaging.
Mayer AT, Natarajan A, Gordon S, Maute R, McCracken M, Ring A, Weissman I, Gambhir SS.
J Nucl Med. 2016 Dec 15.

26)   Isomeric Detergent Comparison for Membrane Protein Stability: Importance of Inter-Alkyl-Chain Distance and Alkyl Chain Length.
Cho KH, Hariharan P, Mortensen JS, Du Y, Nielsen AK, Byrne B, Kobilka BK, Loland CJ, Guan L, Chae PS.
Chembiochem. 2016 Dec 14;17(24):2334-2339.

27)   Feasibility of Obtaining Measures of Lifestyle From a Smartphone App: The MyHeart Counts Cardiovascular Health Study.
McConnell MV, Shcherbina A, Pavlovic A, Homburger JR, Goldfeder RL, Waggot D, Cho MK, Rosenberger ME, Haskell WL, Myers J, Champagne MA, Mignot E, Landray M, Tarassenko L, Harrington RA, Yeung AC, Ashley EA.
JAMA Cardiol. 2016 Dec 14.

28)   Targeting LOXL2 for cardiac interstitial fibrosis and heart failure treatment.
Yang J, Savvatis K, Kang JS, Fan P, Zhong H, Schwartz K, Barry V, Mikels-Vigdal A, Karpinski S, Kornyeyev D, Adamkewicz J, Feng X, Zhou Q, Shang C, Kumar P, Phan D, Kasner M, López B, Diez J, Wright KC, Kovacs RL, Chen PS, Quertermous T, Smith V, Yao L, Tschöpe C, Chang CP.
Nat Commun. 2016 Dec 14;7:13710.

29)   Early-Onset Hypertrophic Cardiomyopathy Mutations Significantly Increase the Velocity, Force, and Actin-Activated ATPase Activity of Human β-Cardiac Myosin.
Adhikari AS, Kooiker KB, Sarkar SS, Liu C, Bernstein D, Spudich JA, Ruppel KM.
Cell Rep. 2016 Dec 13;17(11):2857-2864.

30)   Safety and Tolerability of CSL112, a Reconstituted, Infusible, Plasma-Derived Apolipoprotein A-I, After Acute Myocardial Infarction: The AEGIS-I Trial (ApoA-I Event Reducing in Ischemic Syndromes I).
Michael Gibson C, Korjian S, Tricoci P, Daaboul Y, Yee M, Jain P, Alexander JH, Steg PG, Lincoff AM, Kastelein JJ, Mehran R, D'Andrea DM, Deckelbaum LI, Merkely B, Zarebinski M, Ophuis TO, Harrington RA.
Circulation. 2016 Dec 13;134(24):1918-1930.

31)   Interactive effects of obesity and physical fitness on risk of ischemic heart disease.
Crump C, Sundquist J, Winkleby MA, Sundquist K.
Int J Obes (Lond). 2016 Dec 13.

32)   Engineered Substrate-Specific Delta PKC Antagonists to Enhance Cardiac Therapeutics.
Qvit N, Kornfeld OS, Mochly-Rosen D.
Angew Chem Int Ed Engl. 2016 Dec 12;55(50):15672-15679.

33)   Effect of physical training on the recovery of acute exercise, among patients with cardiovascular disease.
García-Saldivia M, Ilarraza-Lomelí H, Myers J, Lara J, Bueno L.
Arch Cardiol Mex. 2016 Dec 12.

34)   The Influence of Lesion Location on the Diagnostic Accuracy of Adenosine-Free Coronary Pressure Wire Measurements.
Kobayashi Y, Johnson NP, Berry C, De Bruyne B, Gould KL, Jeremias A, Oldroyd KG, Pijls NH, Fearon WF; CONTRAST Study Investigators.
JACC Cardiovasc Interv. 2016 Dec 12;9(23):2390-2399.

35)   Control of cerebral ischemia with magnetic nanoparticles.
Jia JM, Chowdary PD, Gao X, Ci B, Li W, Mulgaonkar A, Plautz EJ, Hassan G, Kumar A, Stowe AM, Yang SH, Zhou W, Sun X, Cui B, Ge WP.
Nat Methods. 2016 Dec 12.

36)   Coronary Artery Development: Progenitor Cells and Differentiation Pathways.
Sharma B, Chang A, Red-Horse K.
Annu Rev Physiol. 2016 Dec 9.

37)   Non-invasive FFRCT revealing severe inducible ischaemia in an anomalous right coronary artery.
Zimmermann FM, Kobayashi Y, Mullen WL, Fearon WF.
Eur Heart J. 2016 Dec 9.

38)   Enhancing reproducibility for computational methods.
Stodden V, McNutt M, Bailey DH, Deelman E, Gil Y, Hanson B, Heroux MA, Ioannidis JP, Taufer M.
Science. 2016 Dec 9;354(6317):1240-1241.

39)   The Influence of Race and Common Genetic Variations on Outcomes After Pediatric Heart Transplantation.
Green DJ, Brooks MM, Burckart GJ, Chinnock RE, Canter C, Addonizio LJ, Bernstein D, Kirklin JK, Naftel DC, Girnita DM, Zeevi A, Webber SA.
Am J Transplant. 2016 Dec 8.

40)   Biomarkers and Coronary Lesions Predict Outcomes after Revascularization in Non-ST-Elevation Acute Coronary Syndrome.
Lindholm D, James SK, Bertilsson M, Becker RC, Cannon CP, Giannitsis E, Harrington RA, Himmelmann A, Kontny F, Siegbahn A, Steg PG, Storey RF, Velders MA, Weaver WD, Wallentin L; PLATO Investigators.
Clin Chem. 2016 Dec 8.

41)   Intronic polyadenylation of PDGFRα in resident stem cells attenuates muscle fibrosis.
Mueller AA, van Velthoven CT, Fukumoto KD, Cheung TH, Rando TA.
Nature. 2016 Dec 8;540(7632):276-279.

42)   Building proteomic tool boxes to monitor MHC class I and class II peptides.
Schumacher FR, Delamarre L, Jhunjhunwala S, Modrusan Z, Phung QT, Elias JE, Lill JR.
Proteomics. 2016 Dec 8.

43)   Nanobodies to Study G Protein-Coupled Receptor Structure and Function.
Manglik A, Kobilka BK, Steyaert J.
Annu Rev Pharmacol Toxicol. 2016 Dec 7.

44)   Genetic variations of aldehyde dehydrogenase 2 and alcohol dehydrogenase 1B are associated with the etiology of atrial fibrillation in Japanese.
Nakano Y, Ochi H, Onohara Y, Sairaku A, Tokuyama T, Matsumura H, Tomomori S, Amioka M, Hironomobe N, Motoda C, Oda N, Chayama K, Chen CH, Gross ER, Mochly-Rosen D, Kihara Y.
J Biomed Sci. 2016 Dec 7;23(1):89.

45)   Reference Standards for Cardiorespiratory Fitness Measured With Cardiopulmonary Exercise Testing Using Cycle Ergometry: Data From the Fitness Registry and the Importance of Exercise National Database (FRIEND) Registry.
Kaminsky LA, Imboden MT, Arena R, Myers J.
Mayo Clin Proc. 2016 Dec 7.

46)   Right-Dominant Unbalanced Atrioventricular Septal Defect: Echocardiography in Surgical Decision Making.
Arunamata A, Balasubramanian S, Mainwaring R, Maeda K, Selamet Tierney ES.
J Am Soc Echocardiogr. 2016 Dec 6.

47)   The BAF45a/PHF10 Subunit of SWI/SNF-like Chromatin Remodeling Complexes is Essential for Hematopoietic Stem Cell Maintenance.
Krasteva V, Crabtree GR, Lessard JA.
Exp Hematol. 2016 Dec 5.

48)   Hypoxia inducible factor stabilization improves defective ischemia-induced angiogenesis in a rodent model of chronic kidney disease.
Schellinger IN, Cordasic N, Panesar J, Buchholz B, Jacobi J, Hartner A, Klanke B, Jakubiczka-Smorag J, Burzlaff N, Heinze E, Warnecke C, Raaz U, Willam C, Tsao PS, Eckardt KU, Amann K, Hilgers KF.
Kidney Int. 2016 Dec 4.

49)   Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity.
Carcamo-Orive I, Hoffman GE, Cundiff P, Beckmann ND, D'Souza SL, Knowles JW, Patel A, Papatsenko D, Abbasi F, Reaven GM, Whalen S, Lee P, Shahbazi M, Henrion MY, Zhu K, Wang S, Roussos P, Schadt EE, Pandey G, Chang R, Quertermous T, Lemischka I.
Cell Stem Cell. 2016 Dec 2.

50)   Patient-Specific iPSC-Derived Endothelial Cells Uncover Pathways that Protect against Pulmonary Hypertension in BMPR2 Mutation Carriers.
Gu M, Shao NY, Sa S, Li D, Termglinchan V, Ameen M, Karakikes I, Sosa G, Grubert F, Lee J, Cao A, Taylor S, Ma Y, Zhao Z, Chappell J, Hamid R, Austin ED, Gold JD, Wu JC, Snyder MP, Rabinovitch M.
Cell Stem Cell. 2016 Dec 2.

51)   Depleting dietary valine permits nonmyeloablative mouse hematopoietic stem cell transplantation.
Taya Y, Ota Y, Wilkinson AC, Kanazawa A, Watarai H, Kasai M, Nakauchi H, Yamazaki S.
Science. 2016 Dec 2;354(6316):1152-1155.

52)   Use of high-intensity statins for patients with atherosclerotic cardiovascular disease in the Veterans Affairs Health System: Practice impact of the new cholesterol guidelines.
Rodriguez F, Lin S, Maron DJ, Knowles JW, Virani SS, Heidenreich PA.
Am Heart J. 2016 Dec;182:97-102.

53)   Temporal trends and factors associated with diabetes mellitus among patients hospitalized with heart failure: Findings from Get With The Guidelines-Heart Failure registry.
Echouffo-Tcheugui JB, Xu H, DeVore AD, Schulte PJ, Butler J, Yancy CW, Bhatt DL, Hernandez AF, Heidenreich PA, Fonarow GC.
Am Heart J. 2016 Dec;182:9-20

54)   Levosimendan in patients with left ventricular systolic dysfunction undergoing cardiac surgery on cardiopulmonary bypass: Rationale and study design of the Levosimendan in Patients with Left Ventricular Systolic Dysfunction Undergoing Cardiac Surgery Requiring Cardiopulmonary Bypass (LEVO-CTS) trial.
Mehta RH, Van Diepen S, Meza J, Bokesch P, Leimberger JD, Tourt-Uhlig S, Swartz M, Parrotta J, Jankowich R, Hay D, Harrison RW, Fremes S, Goodman SG, Luber J, Toller W, Heringlake M, Anstrom KJ, Levy JH, Harrington RA, Alexander JH; LEVO-CTS Investigators.
Am Heart J. 2016 Dec;182:62-71.

55)   Aging of the Immune System. Mechanisms and Therapeutic Targets.
Weyand CM, Goronzy JJ.
Ann Am Thorac Soc. 2016 Dec;13(Supplement_5):S422-S428.

56)   Angina and associated healthcare costs following percutaneous coronary intervention: A real-world analysis from a multi-payer database.
Ben-Yehuda O, Kazi DS, Bonafede M, Wade SW, Machacz SF, Stephens LA, Hlatky MA, Hernandez JB.
Catheter Cardiovasc Interv. 2016 Dec;88(7):1017-1024.

57)   Functional Neurologic Outcomes Change Over the First 6 Months After Cardiac Arrest.
Tong JT, Eyngorn I, Mlynash M, Albers GW, Hirsch KG.
Crit Care Med. 2016 Dec;44(12):e1202-e1207.

58)   Improved walking speed is associated with lower hospitalisation rates in patients in an exercise-based secondary prevention programme.
Grazzi G, Mazzoni G, Myers J, Codecà L, Pasanisi G, Napoli N, Guerzoni F, Volpato S, Conconi F, Chiaranda G.
Heart. 2016 Dec 1;102(23):1902-1908.

59)   Minimally invasive mitral valve repair in situs inversus totalis.
Goldstone AB, Patrick WL, Bilbao MS, Woo YJ.
J Card Surg. 2016 Dec;31(12):718-720.

60)   Predictive models for mortality after ruptured aortic aneurysm repair do not predict futility and are not useful for clinical decision making.
Thompson PC, Dalman RL, Harris EJ, Chandra V, Lee JT, Mell MW.
J Vasc Surg. 2016 Dec;64(6):1617-1622.

61)   Microembolization is associated with transient cognitive decline in patients undergoing carotid interventions.
Hitchner E, Baughman BD, Soman S, Long B, Rosen A, Zhou W.
J Vasc Surg. 2016 Dec;64(6):1719-1725.

62)   Stem cells and interspecies chimaeras.
Wu J, Greely HT, Jaenisch R, Nakauchi H, Rossant J, Belmonte JC.
Nature. 2016 Dec 1;540(7631):51-59.

63)   Power of an Adaptive Trial Design for Endovascular Stroke Studies: Simulations Using IMS (Interventional Management of Stroke) III Data.
Lansberg MG, Bhat NS, Yeatts SD, Palesch YY, Broderick JP, Albers GW, Lai TL, Lavori PW.
Stroke. 2016 Dec;47(12):2931-2937.