Stanford Cardiovascular Institute
and
Duke Cardiovascular Research Center
host the

Stanford-Duke
Cardiovascular Research Symposium

November 29 - 30, 2018

Li Ka Shing Center | Stanford University

| Register Here |

| Download Program |

Day 1
Day 2

Noon - 1:00pm | Registration and badge pickup

Introductory Remarks

1:00pm | Welcome

Joseph Wu, MD, PhD

Director, Stanford Cardiovascular Institute
Simon H. Stertzer, M.D., Professor of Medicine and Radiology
Stanford University School of Medicine

Howard Rockman, MD

Professor of Medicine
Edward S. Orgain Professor of Cardiology, in the School of Medicine
Duke University School of Medicine

Sean M. Wu, MD, PhD

Associate Professor of Medicine and, by courtesy, Pediatrics
Stanford University School of Medicine

1:05pm | Introductory Remarks

Lloyd Minor, MD

The Carl and Elizabeth Naumann Professorship for the Dean of the School of Medicine
Professor of Otolaryngology - Head and Neck Surgery, and, by courtesy, of Neurobiology and Bioengineering
Stanford University School of Medicine

1:10pm | Opening Keynote

Heart & Brain Sciences, Health Equity and the AHA

Ivor Benjamin, MD

AHA President
Medical College of Wisconsin

Google Baseline Project – A Stanford-Duke Collaboration

Chair: Francois Haddad, MD

Clinical Associate Professor, Cardiovascular Medicine
Stanford University School of Medicine

1:45pm

Project Baseline: Convergence of Data & Healthcare

David Maron, MD

Director of Preventative Cardiology
Stanford University School of Medicine

2:05pm

Project Baseline: Return of Results - Seek and Ye Shall Find

Svati Shah, MD, MHS

Associate Professor of Medicine
Duke University School of Medicine

2:25pm

Project Baseline: Participants as Partners - Engage, Educate, Empower

Ken Mahaffey, MD

Director of Stanford Center for Clinical Research
Vice Chair Clinical Research, Department of Medicine
Stanford University School of Medicine

2:45pm | Coffee Break

G Protein-Coupled Receptor Biology Across the Continent

Chair: Helen Blau, PhD

Donald E. and Delia B. Baxter Professor
Director, Baxter Laboratory for Stem Cell Biology
Stanford University School of Medicine

3:05pm

Ubiquitin-dependent regulation of β-adrenergic receptor trafficking and signaling

Sudha Shenoy, PhD

Associate Professor in Medicine and in Cell Biology
Duke University School of Medicine

3:30pm

New Paradigms for Arrestin-Mediated Signaling at GPCRs and Other Receptors

Sudar Rajagopal, MD, PhD

Assistant Professor in Cardiology
Co-Director of Duke Pulmonary Vascular Disease Center
Duke University School of Medicine

3:50pm

β-receptor Subtype Regulation of Cardiotoxicity/Cardioprotection: Just When You Thought it was Safe to go Back in the Water

Dan Bernstein, MD

Alfred Woodley Salter And Mabel Smith Salter Endowed Professor In Pediatrics
Stanford University School of Medicine

4:10pm

Biased GPCR Signaling

Howard Rockman, MD

Professor of Medicine
Edward S. Orgain Professor of Cardiology, in the School of Medicine
Duke University School of Medicine

Lab or Hospital Tour (available on request)

5:00pm | Social Mixer – Bing Dining Hall, Stanford Hospital 3^rd Floor

5:30pm | Symposium Faculty Dinner – Bing Dining Hall, Stanford Hospital 3^rd Floor

7:30am | Arrival and Breakfast

8:00am | Welcome

Bob Harrington, MD

Chair, Dept of Medicine
Arthur L. Bloomfield Professor of Medicine
Stanford University School of Medicine

Keynote Lecture

8:05am |

Chair: Howard Rockman, MD

Professor of Medicine
Edward S. Orgain Professor of Cardiology, in the School of Medicine
Duke University School of Medicine

Structure-aided Drug Discovery for G Protein Coupled Receptors

Brian Kobilka, MD (Includes time for Q&A)

Professor, Molecular & Cellular Physiology
2012 Nobel Laureate
Stanford University School of Medicine

Basic and Translational Approaches to Vascular and Myocardial Biology

Chair: Marlene Rabinovitch, MD

Dwight and Vera Dunlevie Professor in Pediatric Cardiology
Stanford University School of Medicine

8:50am

Genomic Approaches to Discover Novel Drug Targets for Obesity and Insulin Resistance

Erik Ingelsson, MD

Professor of Medicine, Cardiovascular Medicine
Stanford University School of Medicine

9:10am

TREK-1 Affects the Cardiac Injury Response by Modulating Intercellular Crosstalk

Dennis Abraham, MD

Assistant Professor of Medicine
Director of Duke Cardiovascular Physiology Core
Duke University School of Medicine

9:30am | Break

9:40am

Genetic Mechanisms of Coronary Artery Disease: What Can we Learn From GWAS?

Thomas Quertermous, MD

William G. Irwin Professor in Cardiovascular Medicine
Stanford Univeristy School of Medicine

10:00am

The Long and the Short of it: Telomere Length as a Hallmark of Cardiac Failure

Helen Blau, MD

Donald E. and Delia B. Baxter Professor
Director, Baxter Laboratory for Stem Cell Biology
Stanford University School of Medicine

10:20am

Unfolding the Misfolded: Molecular Insights into Cardiac Amyloidosis

Ronglih Liao, MD

Professor of Medicine, Cardiovascular Medicine
Co-Director, Stanford Cardiac Amyloid Center
Stanford University School of Medicine

10:40am | Break

Heart Failure Therapies – Percutaneous, Surgical, and Regenerative Approaches

Chair: Sharon Hunt, MD

Professor Emerita of Medicine, Cardiovascular Medicine
Stanford University School of Medicine

10:50am

Innovative Therapies for Ischemic Cardiomyopathy

Joseph Woo, MD

Norman E. Shumway Professor
Chair, Department of Cardiothoracic Surgery
Stanford University School of Medicine

11:10am

Man vs. Machine: Will Mechanically Assisted Circulation Achieve Its Goals?

Joseph Rogers, MD

Professor of Medicine
Duke University School of Medicine

11:30am

Personalized Medicine in Heart Transplantation

Kiran Khush, MD, MAS

Associate Professor of Medicine, Cardiovascular Medicine
Stanford University School of Medicine

11:50pm

Vascular Approaches to Innate Heart Regeneration

Ravi Karra, MD

Assistant Professor of Medicine
Duke University School of Medicine

12:10pm | Lunch and Poster Viewing / Meet the Professors Lunch

Genome, Transcriptome, and Precision Health

Chair: Nigam Shah, MBBS, PhD

Associate Professor of Medicine (Biomedical Informatics) and of Biomedical Data Science
Stanford University School of Medicine

1:10pm

Pharmacogenomics for Precision Cardiovascular Health

Latha Palaniappan, MD, MS

Professor of Medicine, Primary Care and Population Health
Stanford University School of Medicine

1:30pm

Unexpected Biology of snoRNAs in the Heart

Christopher Lee Holley, MD, PhD

Assistant Professor of Medicine
Assistant Research Professor of Molecular Genetics and Microbiology
Duke University School of Medicine

1:50pm

Population, Medical, and Functional Genomics in the Personal Genome Era

Carlos Bustamante, PhD

Professor of Biomedical Data Science, of Genetics and, by courtesy, of Biology
Stanford University School of Medicine

2:10pm | Coffee Break

State-of-the-Art Approaches to
Detection and Treatment of EP Diseases

Chair: Sanjiv Narayan, MD, PhD

Professor of Medicine, Cardiovascular Medicine
Stanford University School of Medicine

2:20pm

Wearables and Arrhythmias: Where are we Headed?

Mintu Turakhia, MD, MAS

Executive Director, Stanford Center for Digital Health
Associate Professor of Medicine, Cardiovascular Medicine
Palo Alto Veterans Affairs Health Care System

2:40pm

Innovation and the Future of Arrhythmia Therapy

Paul Wang, MD

Professor of Medicine, Cardiovascular Medicine
Stanford University School of Medicine
Editor of Circulation: Arrhythmia and Electrophysiology

Best Abstract Trainee Presentations

Chair: Elan Burton, MD

Clinical Assistant Professor, Cardiothoracic Surgery
Stanford University School of Medicine

3:00pm

Molecular Mechanisms of Angiotensin Receptor Activation and Biased Signaling

Laura Wingler, PhD

Postdoctoral Scholar, Lefkowitz Lab
Duke University School of Medicine

3:13pm

Parental Disease and Over-transmission of Genetic Risk for Diabetes are Related to Congenital Heart Disease in Offspring

Catherine Tcheandjieu

Priest Lab
Stanford University School of Medicine

3:26pm

On the intertwined nature of endothelium and muscle: defining new signaling paradigms in peripheral artery disease

Hasan Abbas

Kontos Lab
Duke University School of Medicine

3:38pm

Modeling hypertrophic cardiomyopathy caused by mutations in beta-myosin using human induced pluripotent stem cell derived cardiomyocytes (iPSC-CMs)

Alison Schroer

Bernstein Lab / Pruitt Lab (UCSB)
Stanford University School of Medicine

3:50pm | Coffee Break

Population, Quality, and Outcomes in Cardiovascular Care

Chair: Paul Heidenreich, MD

Professor of Medicine, Cardiovascular
Palo Alto Veterans Affairs Health Care System

4:00pm

Evaluating Precision Medicine

Mark Hlatky, MD

Professor of Health Research and Policy (Health Services Research) and of Medicine (Cardiovascular Medicine)
Stanford University School of Medicine

4:20pm

Closing the Gaps in Care: What’s Next in Implementation Science?

Eric Peterson, MD

Fred Cobb, MD, Professor of Medicine
Duke University School of Medicine

4:40pm

Controversies in Economics of Precision Medicines

Kevin Schulman, MD

Professor of Medicine, Associate Chair of Business Development and Strategy, Department of Medicine
Stanford University School of Medicine

5:00pm | Wine and Cheese Reception and Poster Session with Presentation of Poster Awards

Symposium Keynote Speaker

Brian Kolbilka, MD

2012 Nobel Prize in Chemistry

Stanford-DukeCardiovascular Research Symposium

Day 1

Day 2

Noon - 1:00pm | Registration and badge pickup

Introductory Remarks

1:00pm | Welcome

Joseph Wu, MD, PhD

Howard Rockman, MD

Sean M. Wu, MD, PhD

1:05pm | Introductory Remarks

Lloyd Minor, MD

1:10pm | Opening Keynote

Heart & Brain Sciences, Health Equity and the AHA

Ivor Benjamin, MD

Google Baseline Project – A Stanford-Duke Collaboration

Chair: Francois Haddad, MD

1:45pm

Project Baseline: Convergence of Data & Healthcare

David Maron, MD

2:05pm

Project Baseline: Return of Results - Seek and Ye Shall Find

Svati Shah, MD, MHS

2:25pm

Project Baseline: Participants as Partners - Engage, Educate, Empower

Ken Mahaffey, MD

2:45pm | Coffee Break

G Protein-Coupled Receptor Biology Across the Continent

Chair: Helen Blau, PhD

3:05pm

Ubiquitin-dependent regulation of β-adrenergic receptor trafficking and signaling

Sudha Shenoy, PhD

3:30pm

New Paradigms for Arrestin-Mediated Signaling at GPCRs and Other Receptors

Sudar Rajagopal, MD, PhD

3:50pm

β-receptor Subtype Regulation of Cardiotoxicity/Cardioprotection: Just When You Thought it was Safe to go Back in the Water

Dan Bernstein, MD

4:10pm

Biased GPCR Signaling

Howard Rockman, MD

Lab or Hospital Tour (available on request)

5:00pm | Social Mixer – Bing Dining Hall, Stanford Hospital 3rd Floor

5:30pm | Symposium Faculty Dinner – Bing Dining Hall, Stanford Hospital 3rd Floor

8:00am | Welcome

Bob Harrington, MD

8:05am |

Chair: Howard Rockman, MD

Structure-aided Drug Discovery for G Protein Coupled Receptors

Brian Kobilka, MD (Includes time for Q&A)

Chair: Marlene Rabinovitch, MD

8:50am

Genomic Approaches to Discover Novel Drug Targets for Obesity and Insulin Resistance

Erik Ingelsson, MD

9:10am

TREK-1 Affects the Cardiac Injury Response by Modulating Intercellular Crosstalk

Dennis Abraham, MD

9:40am

Genetic Mechanisms of Coronary Artery Disease: What Can we Learn From GWAS?

Thomas Quertermous, MD

10:00am

The Long and the Short of it: Telomere Length as a Hallmark of Cardiac Failure

Helen Blau, MD

10:20am

Unfolding the Misfolded: Molecular Insights into Cardiac Amyloidosis

Ronglih Liao, MD

Chair: Sharon Hunt, MD

10:50am

Innovative Therapies for Ischemic Cardiomyopathy

Joseph Woo, MD

11:10am

Man vs. Machine: Will Mechanically Assisted Circulation Achieve Its Goals?

Joseph Rogers, MD

11:30am

Personalized Medicine in Heart Transplantation

Kiran Khush, MD, MAS

11:50pm

Vascular Approaches to Innate Heart Regeneration

Ravi Karra, MD

Chair: Nigam Shah, MBBS, PhD

1:10pm

Stanford-Duke
Cardiovascular Research Symposium

5:00pm | Social Mixer – Bing Dining Hall, Stanford Hospital 3^rd Floor

5:30pm | Symposium Faculty Dinner – Bing Dining Hall, Stanford Hospital 3^rd Floor